Indian Journal of Chemistry;

Total visitors:7150 since 8-12-2010

Sect. B: Organic Chemistry including Medicinal Chemistry

VOL. 49B


December 2010







A new quinone from Maesa indica (roxb.)A.dc, (myrsinaceae)


A new benzoquinone, kiritiquinone 2,5-dihydroxy-6-methyl-3-(henicos-16-enyl)-1,4-benzoquinone, has been isolated from the fruits of Maesa indica (Roxb.) A.DC.








Gina R Kuruvilla, M Neeraja, A Srikrishna*

 G S R Subba Rao, A V S Sudhakar &
Padma Venkatasubramanian


Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India









Synthesis and biological screening of novel derivatives of 3-(N-substituted carboxamidoethyl­thio)-(4H)-1,2,4-triazoles


3-Mercapto-(4H)-1,2,4-triazole has been synthesized from
1-formylthiosemicarbazide. Different N-substituted β-chloro­propionamides have been prepared by reacting substituted amines with β-chloropropionylchloride. Different N-sub­stituted β-chloropropionamides have been condensed with 3-mercapto-(4H)-1,2,4-triazole in basic medium to obtained various 3-(N-substituted carboxamidoethylthio)-(4H)-1,2,4-triazoles.








Anil M Manikrao*, Ravindra A Fursule,

 K S Rajesh , Harish K Kunjwani

 & Prafulla M Sabale


Department of Pharmaceutical Chemistry, Parul Institute of Pharmacy, Limda, Vadodara 391 760, India















Total synthesis of three natural products: Decyl 8-hydroxyheptadecanoate, undecyl hexadecanoate and 2,3-dihydroxypropyl hexadecanoate


First syntheses of decyl 8-hydroxy-heptadecanoate 1 and undecyl hexadecanoate 2 via utilization of microwave energy have been achieved and a new synthesis of 2,3-dihydroxy­propyl hexadecanoate 3 has also been accomplished from readily available starting compound hexadecanol.






Ashima Singh, M L Sharma

& Jasvinder Singh*


Department of Chemistry and Centre for Advanced Studies in Chemistry, Panjab University,
Chandigarh 160 014, India










Aluminium nitrate as an efficient and reusable catalyst for the three components one-pot Mannich reaction: Synthesis of β-amino carbonyl compounds


Three components one-pot Mannich reaction of aromatic ketones, aromatic aldehydes and aromatic amines has been efficiently catalysed by recyclable aluminium nitrate at ambient temperature to give various β-amino carbonyl compounds in high yields.




Min Wang*, Yan Liang & Zhiguo Song


College of Chemistry and Chemical Engineering, Bohai University, Jinzhou 121000, P. R. China









Quantitative structure activity relationships for the nematicidal activity of  4-amino-5-substituted aryl-3-mercapto-(4H)-1,2,4-triazoles


The relationship between the structure of a series of 4-amino-5-substituted aryl-3-mercapto-(4H)-1,2,4-triazoles and their nematicidal activity against M. incognita and R. reniformis has been studied using physicochemical parameters of the molecules.




Bijul Lakshman A, R L Gupta* & D Prasad


Division of Agricultural Chemicals, Division of Nematology, Indian Agricultural Research Institute,

New Delhi 110 012, India















Synthesis of benzothiazole appended b-lactams through[2+2]-cycloaddition reaction












Arasampattu S Nagarajan, D Kathirvelan,

 M Pramesh & Boreddy S R Reddy*


Industrial Chemistry Laboratory, Central Leather Research Institute, Chennai 600 020, India









Synthesis of N-1-(3,5-dimethyl-4-isoxozolyl)-3-(4-aryl-5-thioxo-4,5-dihydro-1-H–1,2,4-triazol–3-yl)­propanamides as possible antitumor agents


Synthesis of N-1 (3, 5-dimethyl-4-isoxazolyl)-3-(4-aryl-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)-propanamides 7 have been accomplished from 4-amino-3,5-dimethylisoxazole 1 in five steps. The structural elucidation of the synthesized compounds has been performed by IR, 1H NMR and mass spectroscopic data besides elemental analyses.







Ch V Narsimha Reddy, S Raju,

M Nagi Reddy & E Rajanarendar*


Department of Chemistry, Kakatiya University, Warangal 506 009, India


















Synthesis and bioactivity evaluation of pyrazolone derivatives


A series of 3-methyl pyrazolone derivatives have been synthesized and characterized. All the compounds have shown significant analgesic and anti inflammatory activity.






Mariappan G*, Saha B P,

 Sutharson L & Haldar A


Department of Pharmaceutical Chemistry, Himalayan Pharmacy Institute, Majhitar, East Sikkim 737 136, India









Studies of antimicrobial activity of picryl amino pyridine N-oxides


Biologically active picryl amino pyridines and their N-oxide have been successfully synthesized and screened for their antimicrobial potency to set up the structure activity relationships and found to possess better antibacterial activity than antifungal activity.





D M Badgujar, m B Talawar,

S N Asthana & P P Mahulikar*


School of Chemical Sciences, North Maharashtra University, Jalgaon 425 001, India








High atom efficient and environment-friendly preparation of herbicides bromoxynil and ioxynil


High atom efficient and environment-friendly preparation of herbicides bromoxynil and ioxynil using bromide/bromate and iodide/iodate couple as halogenating reagent in water at room temperature is described.





Adimurthy Subbarayappa*,

 Girdhar Joshi & Rajendra D Patil


Central Salt & Marine Chemicals Research Institute, (CSIR), G. B. Marg, Bhavnagar 364 002, India









Annual Index






Authors for correspondence are indicated by (*)