Indian Journal of Chemistry

Sect. B: Organic Chemistry including Medicinal Chemistry

 

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VOL. 50B

NUMBER 1

January 2011

CONTENTS

Rapid Communication

 

 

 

73

Enantiospecific approach to AB-ring system of the diterpenes fusicoccanes

 

Enantiospecific synthesis of AB ring system of the 5-8-5 tri­cyclic diterpenes fusicoccanes has been described.

 

 

 

 

 

A Srikrishna*  & Gopalasetty Nagaraju

 

Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India

 

 

 

 

Papers

 

 

 

77

An efficient synthesis of symmetrical N,N′-alkyl­idene bisamides catalyzed by phosphor­tung­stic acid

 

Symmetrical N,N-alkylidene bisamides have been synthesized by condensation of aromatic aldehydes and amides in the presence of phosphotungstic acid as a catalyst under thermal and neat microwave irradiation conditions.

 

 

 

 

 

 

Gurusamy Harichandran*, Savarimuthu DavidAmalraj & Ponnusamy Shanmugam

 

Department of Polymer Science, University of Madras, Guindy Campus, Chennai 600 025, India

 

 

 

 

 

 

 

 

 

 

 

 

 

83

Synthesis, configurational analysis and antimicro­bial activity of imidazolidinone, thiazolidinone and isoxazolone derivatives of 9,10-phenanthrene­quinone

 

A facile synthesis of imidazolidinone, thiazolidinone and isoxazolone derivatives has been described by Knoevenagel type condensation reactions of 9,10-phenanthrenequinone with active methylene heterocycles/compounds. The products have been characterized by spectral data. Semiempirical studies have been performed to understand the stereochemical course of the reaction. Some of the synthesized products have been screened for antimicrobial activity.

 

 

 

 

 

 

 

 

 

Komal Arora, Sonali Verma, Rahul Joshi, P Pardasani & R T Pardasani*

 

Department of Chemistry, University of Rajasthan, Jaipur 302 055, India

 

 

 

 

 

 

 

89

Conventional as well as microwave assisted synthesis and antimicrobial screening of 4-aryl-3-chloro-1-[(5-nitroindazol-1-yl) acetamido]-2-oxo-azetidines

 

Several new 4-aryl-3-chloro-1-[(5-nitroindazol-1-yl) aceta­mido]-2-oxo-azetidines, 4a-l have been synthesized from 2-(5-nitroindazol-1-yl) acetamidyl amino arylidenes, 3a-l. The reactions have been carried out by both conventional as well as microwave method. All the synthesized compounds have been screened for their antibacterial and antifungal activity against some selected micro organisms.

 

 

 

 

 

 

Where Ar  = Substituted aryl groups

 

 

 

 

 

Apoorva Upadhyay*, S K Srivastava, S D Srivastava & R Yadav

 

Synthetic Organic Chemistry Laboratory, Department of Chemistry, Dr. H. S. Gour University

 (A Central University), Sagar 470 003, India

 

 

 

 

 

 

 

 

 

Notes

 

 

 

98

Synthesis of 4-(3H)-quinazolinones by microwave assisted tandem reaction and evaluation of their antibacterial and antifungal activities

 

A one pot synthesis of quinazolinone derivatives from the reaction of anthranilic acid and primary aromatic amines with Vilsmeier reagent (DMF/POCl3) has been carried out under microwave irradiation. All the synthesized compounds have been screened for their in vitro antibacterial and antifungal activity.

 

 

 

 

 

M Gnana Ruba Priya, Y Zulykama, K Girija, S Murugesh & P T Perumal*

 

Department of Biotechnology, Sastra University,  Thanjavur 613 402, India

 

 

 

 

 

 

 

103

Application of 2-(1H-benzotriazol-1-yl)-1,1,3,3-te­tra­methyluronium tetrafluoroborate (TBTU) for the synthesis of acid azides

 

Acid azides have been efficiently prepared from carboxylic acids employing peptide coupling agent TBTU. The protocol is extended to synthesize urethane protected amino acid azides also.

 

 

 

 

Shankar A Naik, Lalithamba H S &  Vommina V Sureshbabu*

 

Peptide Research Laboratory, Department of Studies in Chemistry, Central College Campus,

Bangalore University, Dr. B. R. Ambedkar Veedhi, Bangalore 560 001, India

 

 

 

 

 

 

 

110

Green synthesis of 2-amino-5-substituted-1,3,4-oxadiazoles at the platinum anode in acetic acid

 

The electroorganic synthesis of 2-amino-5-substituted-1,3,4-oxadiazoles from the anodic oxidation of semicarbazone have been carried out at platinum anode in acetic acid under constant potential electrolysis in an undivided cell.

 

 

 

 

Laxmi Kant Sharma, Sushma Singh & R K P Singh*

 

Electrochemical Laboratory of Green Synthesis, Department of Chemistry,

University of Allahabad, Allahabad 211 002, India

 

 

 

 

 

 

 

 

 

 

 

 

 

115

Phenolic constituents from the galls of Pistacia integerrima Stewart

 

Phytochemical investigation of the galls of Pistacia integer­rima Stewart (Pistaceaceae) has yielded three new phyto­constit­uents characterized as 14′-phenoxytetradecanyl 3,5-dihydroxybenzo­ate (pistiphloroglucinyl ester) 2, 4′-phenoxy-n-butyl-1′-(3-oxy-5-hydroxy) -benzoic acid (pistaciaphenyl ether) 3 and 3′-(1,3-dihydroxy-5-phenoxy-1′,5′-dimethoxy­benzene (pisticiphloro­glucin­yl ether) 4 along with the known compound ß- sitosterol 1.

 

 

2

3

4

 

 

Shamim Ahmad, Mohammed Ali* & Shahid H Ansari

 

Phytochemical Research Laboratory, Department of Pharmacognosy and Phytochemistry,

Faculty of Pharmacy, Jamia Hamdard, Hamdard University, New Delhi 110 062, India

 

 

 

 

 

 

 

119

An efficient synthesis of 3-chloromethyl-1,2-benzi­soxa­zoles via modified Boekelheide rearrange­ment

 

An efficient and simple method for preparation of 3-chloromethyl-1,2-benzisoxazoles by modified Boekelheide rearrangement using phosphorous oxychloride and TEA in moderate to good yield.

 

 

 

Veera Reddy Arava*, Laxminarasimhulu Gorentla,

Uday Bhaskara Rao Siripalli & Pramod Kumar Dubey

 

R & D Laboratories, SUVEN Life Sciences Ltd., #18, Phase III, Jeedimetla, Hyderabad 500 055, India

 

 

 

 

 

 

 

 

 

 

 

 

 

126

A convenient and simple transformation of acid hydrazides to N,N′-diacylhydrazines with Hg (OAc)2 under solid state conditions

 

A highly efficient and practical methodology for the trans­formation of acid hydrazides 1 to N,N′-diacylhydrazines 2 is described under solid state conditions at RT utilizing inexpen­sive and easily available reagent Hg(OAc)2 with good yields

 

 

 

K Mogilaiah*, E Anitha , K Shiva Kumar & R Shiva Prasad

 

Department of Chemistry, Kakatiya University, Warangal 506 009, India

 

 

 

 

 

Authors for correspondence are indicated by (*)