Indian Journal of Chemistry

 

Sect. B: Organic Chemistry including Medicinal Chemistry

 

http://www.niscair.res.in; http://nopr.niscair.res.in

Total visitors: 6684 since 09-03-2012

 

VOL. 51B

NUMBER 3

March 2012

 

CONTENTS

 

Rapid Communication

 

 

 

 

 

481

An enantiospecific synthesis of a crinipellin

Enantiospecific synthesis of a crinipellin, starting from campholenaldehyde has been described.

 

 

 

 

 

 

 

 

 

A Srikrishna* & V Gowri

 

Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India

 

 

 

 

 

 

 

 

 

 

Papers

 

 

 

 

 

 

 

 

 

486

Synthesis of 5-oxo-1-substituted tetrazoles derived from amino acids

 

An application of amino acid derived isocyanates in the synthesis of 5-oxo-tetrazoles is described. The protocol has been extended for the insertion of tetrazolone in side chains of the Asp/Glu.

 

 

 

 

 

G Nagendra, N Narendra & Vommina V Sureshbabu*

 

aPeptide Research Laboratory, Department of Studies in Chemistry, Central College Campus, Bangalore University,
Dr B R Ambedkar Veedhi, Bangalore 560 001, India

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

493

Synthesis and anticancer activity of 3,5-diaryl-1,2,4-oxadiazole derivatives

 

Condensation of chlorobenzamidoxime with chloro­s ubstituted benzoyl chloride gave 3,5 Diaryl-1,2,4-oxa­diazole derivatives in a single step. These were screened for their anticancer activity.

 

 

 

 

 

 

 

 

 

 

Mrityunjoy Kundu*, Jagadish Singh, Brijesh Singh, Tirtha Ghosh, B C Maiti & T K Maity

 

Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur 495 009, India

 

 

 

 

 

 

498

AgOTf as an alternative catalyst for the regioselective cyclization of 2-(alkynyl)benzyl alcohols: Synthesis and biological evaluation of phthalans

 

The synthesized compounds have been studied for antimicrobial and anticancer activity.

 

 

 

 

 

 

 

 

 

 

Chandrasekaran Praveen, Chandran Iyyappan, Paramasivan T Perumal* & K Girija

 

Organic Chemistry Division, Central Leather Research Institute, Chennai 600 020, India

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

508

Synthesis, characterization and antimicrobial screening of novel quinoline-thiazole derivatives

 

 

 

 

 

 

 

 

N C Desai*, Niraj Shihory, Kiran Rajpara & Amit Dodiya

 

Division of Medicinal Chemistry, Department of Chemistry, Mahatma Gandhi Campus, Bhavnagar University, Bhavnagar 364 002, India

 

 

 

 

 

 

 

 

 

 

514

Synthesis and antimicrobial activity of some new 3-chloro-6-substituted-N-(substituted 2H-[1,3]oxazino­[6,5-b]quinolin-3-(4H,5aH,9aH)-yl) benzo[b]thiophene-2-carboxamides

 

Some new 3-chloro-6-substituted-N-(6-substituted 2H-[1,3]Oxazino [6,5-b]quinolin-3-(4H,5aH,9aH)-yl)­benzo­[b]thiophene-2-carbox­ami­des have been synthe­sized and screened for their antimicrobial activity.

 

 

 

 

 

 

 

 

B V Guruprasad & B H M Mruthyunjayaswamy*

 

Department of Studies and Research in Chemistry. Gulbarga University, Gulbarga 585 106, India

 

 

 

 

 

 

 

 

 

 

521

Synthesis of new 2-(substituted)-5-methyl-2,3-di­hydro-1,3,2 λ5- benzoxazaphosphol-2-ones

 

 

 

 

 

 

 

C Venkateswarlu, P V V Satynarayana, C V Nageswara Rao* & C Naga Raju

 

Department of Chemistry, K V R College, Nandigama 521 185, India

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Notes

 

 

 

 

 

 

 

 

 

525

Microwave assisted green synthesis of novel spiro isoxazolidine derivatives with α-chloro nitrones

 

Microwave assisted 1,3-dipolar cycloaddition reaction of α-chloro nitrones to novel α-N-methyl and α-N-phenylfuran derivative affords exclusively single regioselective 5-spiro isoxazolidines while the same reaction with α-methylene-γ-butyrolactone affords two diastereomeric 5-spiro isoxazolidines with high selectivity.

 

 

 

 

 

 

 

Bhaskar Chakraborty* & Prawin Kumar Sharma

 

Organic Chemistry Laboratory, Sikkim Government College, Gangtok 737 102, India

 

 

 

 

 

 

 

 

 

 

531

Synthesis of 2-aryl-5-(benzofuran-2-yl)-thiazolo[3,2-b][1,2,4]triazoles using green procedures and their antibacterial activity

 

3-Aryl-5-(benzofuran-2-yl)acylthio-1,2,4-triazoles 1a-h on cyclisation using polyphosphoric acid under microwave irradiations give 2-aryl-5-(benzofuran-2-yl)-thiazolo[3,2-b][1,2,4]triazoles 2a-h. The antibacterial activity of these compounds has been described.

 

 

 

 

 

 

Komal Jakhar & J K Makrandi*

 

Department of Chemistry, Maharshi Dayanand University,  Rohtak 124 001, India

 

 

 

 

 

 

 

 

 

 

 

 

 

 

537

One-pot, multicomponent synthesis of 4H-pyrano[2,3-c]pyrazoles in water at 25°C

Several pyranopyrazoles are synthesized by an iodine catalyzed four component reaction at 25°C in water. The yields are excellent; procedure is simple, efficient and environmentally benign.

 

 

 

 

 

 

M B Madhusudana Reddy & M A Pasha*

 

Department of Studies in Chemistry, Bangalore University, Central College Campus, Bengaluru 560 001, India

 

 

 

 

 

 

 

Authors for correspondence are indicated by (*)