Indian Journal of Chemistry

 

Sect. B: Organic Chemistry including Medicinal Chemistry

http://www.niscair.res.in; http://nopr.niscair.res.in

Total visitors: 16745 since 07-03-2013

 

VOL. 52B

NUMBER 3

March 2013

 

CONTENTS

 

Papers

 

 

 

 

379

Economical route for oxidative cleavage of double bond to synthesize taxol side chain

 

 

 

 

 

Sumati Bhatia, Sukhdev Singh, Rajesh Kumar, Amit Kumar, Carl E Olsen & Ashok K Prasad*

 

Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi 110 007, India

 

 

 

 

 

 

 

387

A simple and straightforward method for one-pot synthesis of 2,4,5-triarylimidazoles using titanium dioxide as an eco-friendly and recyclable catalyst under solvent-free conditions

 

A simple, straightforward and cost-effective method for the efficient synthesis of 2,4,5-triarylimidazoles in good to excellent yield using titanium dioxide as an inexpensive and recyclable heterogeneous catalyst by three-component, one-pot condensation of 1,2-diketones, aryl aldehydes and ammonium acetate under solvent-free conditions is reported.

 

 

 

 

 

Goutam Brahmachari* & Suvankar Das

 

Laboratory of Natural Products & Organic Synthesis, Department of Chemistry, Visva-Bharati University,
Santiniketan 731 235, India

 

 

 

 

 

 

 

 

 

 

 

 

 

394

Resolution of (RS)-Binol through co-crystal forma­tion with 3-n-propyl-4-((R/S)-1˘-phenylethyl­amino)­butanoic acid

 

 

 

 

 

 

 

Bhairab Nath Roy*, Girij Pal Singh, Piyush Suresh Lathi, Rangan Mitra, Naba K Nath,
A Kalyanachakravarthi & Ashwini Nangia

 

Chemical Research Department, Lupin Research Park, Lupin Ltd., Survey No. 46A/47A, Nande Village, Mulshi Taluka,
Pune 411 042, India

 

 

 

 

 

 

 

405

Synthesis and antibacterial evaluation of bromo phenyl substituted carbazoles

 

 

 

 

 

 

T Indumathi, T Brant, M Zeller & K J Rajendra Prasad*

 

Department of Chemistry, Bharathiar University, Coimbatore 641 046, India

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

414

Solvent free microwave assisted synthesis and evaluation of potent antimicrobial activity of 1,11H-pyrimido[4,5-a]carbazol-2-ones, 1,11H-pyrimido                         [4,5-a]carbazol-2-thiones and pyrazolo[3,4-a]carbazoles

 

The synthesis of 1,11H-pyrimido[4,5-a]carbazol-2-ones, 1,11H-pyrimido[4,5-a]carbazol-2-thiones and pyrazolo[3,4-a]carbazoles is described. Compounds 2, 3 and 4 have been screened for their antimicrobial activity.

 

 

 

 

 

R Velmurugan, A V Vijayasankar & M Sekar*

 

Post Graduate and Research Department of Chemistry, Sri Ramakrishna Mission Vidyalaya
College of Arts and Science, Coimbatore 641 020, India

 

 

 

 

 

 

 

 

Notes

 

 

 

 

 

 

422

Synthesis, characterisation and anthelmintic activity of 3-(4-acetyl-5-phenyl-4,5-dihydro-1,3,4-oxadiazol-2-yl)- 2H-chromen-2-one derivatives

 

Synthesis of 3(4-acetyl-5-phenyl-4,5-dihydro 1,3,4 oxadiazol-2-yl) 2H-chromene-2-one derivatives have been carried out and their anthelmintic activity has been studied.

 

 

 

 

 

B Naga Sudha, C Sridhar, V Girija Sastry, Y S R Reddy, Owk Sreevidya, S Lavanya,
V Asha Jyothi, V Nagesh, Saikat Sen & Raja Chakraborty
*

 

Department of Pharmaceutical Chemistry, C.E.S. College of Pharmacy, Kurnool 518 218, India

 

 

 

 

 

 

428

Aminated poly(vinyl chloride): An efficient green catalyst for Knoevenagel condensation reactions

 

Commercially available poly(vinyl chloride) has been modified with ethylene diamine to give a highly efficient reusable organocatalyst for Knoevenagel condensations under green conditions.

 

 

 

 

G Rajesh Krishnan, K Sree Niveditha & K Sreekumar*

 

Department of Applied Chemistry, Cochin University of Science and Technology, Cochin 682 022, India

 

 

 

 

 

 

 

 

 

 

 

 

 

432

MW assisted synthesis of some pyrazoles containing benzotriazole moiety: An environmentally benign approach

 

The present paper reports MW assisted synthesis of pyrazoles containing benzotriazole moieties 4a-n by cyclocondensation of substituted chalcones 3a-n with hydrazide of benzotriazole 2 in presence of glacial acetic acid (GAA). The synthesized compounds have been characterized by their IR, 1H NMR and mass spectral studies. These compounds have also been evaluated for their antibacterial and antifungal activities against various microbes.

 

 

 

 

 

 

 

 

 

 

               

 

 

 

 

 

 

Urvashi Tiwari, Chetna Ameta, Manish K Rawal, Rakshit Ameta & Pinki B Punjabi*

 

Microwave Chemistry Laboratory, Department of Chemistry, University College of Science,
M. L. Sukhadia UniversityUdaipur 313 001, India

 

 

 

 

 

 

 

 

 

 

 

 

 

440

Synthesis and antimicrobial activity of 2-cyclopropyl [1,8]naphthyridine-3-carboxylic acid (4-phenyl-2-thioxo-thiazol-3-yl)-amides, [1,3,5]triazine, [1,3,4]­thia­diazole-2-thiol, [1,2,4]triazole-3-thiol and cou­marin derivatives

 

2-Cyclopropyl-[1,8]naphthyridine-3-carboxylic acid ethyl ester 1 reacts with 99% hydrazine hydrate, to yield 2-cyclopropyl-[1,8]naphthyridine-3-carboxylic acid hydrazide 2, which further reacts with carbon disulphide in the presence of potassium hydroxide solution to yield compound 3. Compound 3 reacts with 99% hydrazine hydrate to offer 4-amino-5-(2-cyclopropyl-[1,8]naphthyridin-3-yl)-4H-[1,2,4]triazole-3-thiol 4. Compound 4 is converted to 5 by reaction with phenacyl bromides. On other hand compound 4 on treatment with oxalyl chloride in the presence of triethyl amine provides 6. Compound 3 on treatment with acetic acid in water gives compound 7. On the other hand compound 3 on treatment with phenacyl bromides provides compound 8. Compound 1 reacts with guanidine hydrochloride to yield compound 9 which reacts with aromatic nitriles to offer compound 10.

 

 

 

 

A Narender, M Thirumala Chary*, E Laxminarayana & V Haripriya

 

JNTUH College of Engineering, Nachupally, Karimnagar 505 501, India

 

 

 

 

 

 

 

448

Synthesis of some novel pyrido[2,3-d]pyrimidine derivatives and their antimicrobial investigations

 

 

 

 

 

 

Sangeeta Bhargava* & Lokesh K Rajwanshi

 

Department of Chemistry, University of Rajasthan, Jaipur 302 004, India

 

 

 

 

 

Authors for correspondence are indicated by (*)