Rapid Communications

1711

A simple and efficient tetrahydropyranylation using N-bromosuccinamide

IPC: Int.Cl.⁷ C 07 C 239/06

Biswanath Das*, M Ravinder Reddy, N Ravindranath, V Saidi Reddy & K Venkateshwarlu

Papers

1713

Synthesis in the field of podophyllotoxin and related analogues : Part XII — Synthesis of benzodioxan analogue of didemethoxy-b-apopicropodophyllin

IPC: Int.Cl.⁷ C 07 D 315/00

Total synthesis of didemethoxy-b-apopicropo­dophyllin 15 has been achieved via Stobbe condensation of 6.

S Shashikanth* & Ganesh L Hegde

1721

A rapid synthesis of dipeptidyl urea acids employing p-nitrophenyl-(9-fluorenylmethoxy­carbonylamino)methyl carbamates

IPC: Int.Cl.⁷ C 07 K 1/00

A rapid and efficient protocol for the synthesis of dipeptidyl urea acids employing p-nitrophenyl-(9-fluorenylmethoxycarbonylamino)methyl carbamates as coupling agents has been described.

1729

A novel synthesis of bromomethoxy disubstituted derivatives of benzocyclobutenone

IPC: Int.Cl.⁷ C 07 C 13/00

Flash vacuum pyrolysis of disubstituted ortho methyl aromatic acid chlorides has been used to prepare corresponding benzocyclobutenone derivatives.

Synthesis and characterization of 3-[2-(2-aminoethylamino) ethylamino]propyl-1-silatranes

IPC: Int.Cl.⁷ C 01 B 33/00

3-[2-(2-Aminoethylamino) ethylamino]propyl-1-sila­t­ranes have been synthesized in high yields ranging from 87– 93% by transesterification of 3-[2-(2-amino­ethylamino)ethylamino] propyltrimethoxysilane with different trialkanolamines and characterized on the basis of elemental and spectral analyses. Their ligating behaviour with transition metal halides has been examined.

where m = 3, n = 2

Shailesh C Verma, M Nasim* & P S Venkataramani

1743

Synthesis of 4¢-O- azomethino-d-glucopyranosides

IPC: Int.Cl.⁷ C 07 H 3/02

The synthesis of 4¢-O-azomethino-d-gluco­pyrano­sides by the Koenigs-Knorr method along with spectral data have been reported.

V N Ingle*, U G Upadhyay & S T Kharche

1748

Superoxide induced deprotection of 1,3-dithiolanes : A convenient method of dedithio­acetalization

IPC: Int.Cl.⁷ C 07 D 339/02

Tetraethylammonium superoxide, generated in situ by the phase transfer reaction of potassium superoxide and tetraethylammonium bromide, brings about an easy deprotection of a variety of 1,3-dithiolanes of carbonyl compounds under significantly mild reaction conditions at room temperature.

Ajay Kumar Shukla, Manjusha Verma & Krishna Nand Singh*

1753

NMR spectral studies of some N-aroyl hydrazones

IPC: Int.Cl. G 01 R 33/46, C 07 D 211/00

¹H and ¹³C NMR spectra have been recorded for some N-aroyl (benzoyl, salicyloyl) hydrazones 1-9 derived from piperidin-4-ones and tetrahydrothiopyran-4-one and analysed.

A Manimekalai*, B Senthil Sivakumar &

T Maruthavanan

1758

Distal effect on mass spectral fragmentations of glycolamide esters of 6-methoxy-2-naphthylacetic acid (6-MNA) and the crystal structure of N,N´ -dimethylglycolamide ester of 6-MNA

IPC: Int.Cl.⁷ C 07 C 61/13

Mass spectral fragmentation pattern of glycolamide esters of 6-MNA is influenced by distal amide functionality. Crystal structure reveals specific conformation of the molecule.

Pritam Dev Sharma*, Lalit Kumar Wadhwa, Senthil Kumar Chandiran, Tejvir Singh & Paloth Venugopalan

1765

Synthesis of some new fluorine containing 1,3,4-oxadiazole derivatives as potential antibacterial and anticancer agents

IPC: Int.Cl.⁷ C 07 D 271/00 // A 61 31/04, 35/00

K Subrahmanya Bhat, M S Karthikeyan,

B Shivarama Holla* & N Suchetha Shetty

1770

Synthesis and antiviral activity of furo­benzo­pyrones

IPC: Int.Cl.⁷ C 07 D 311/04 // A 61 P 31/12

V K Pandey*, V K Singh & M Tandon,

M N Joshi & S K Bajpai

Notes

1774

Synthesis of novel 6-substituted-aminopyridin-2(H)-ones

IPC: Int. Cl.⁷ C 07 D 211/00

Compounds 4 and 5 when subjected to azo coupling with aryldiazonium chlorides furnish two isomers 6-substituted-amino - 4-(4-ethoxyphenyl)-1-phenyl-3-(aryl­­azo)­pyridin-2(H)-ones 6a-j and 7a-j and 6-substi­tuted-amino - 4-(4-ethoxyphenyl)-1-phenyl-5-(aryl­a­zo)­­pyridin-2(H)-ones 6k-t and 7k-t. Mannich reaction with 4 and 5 gives single product 6-substituted-amino-4-(4-ethoxyphenyl)-1-phenyl-3-(amino­methyl)­­pyridin-2(H)-ones 8a-b and 9a-b.

A K Patel & N B Patel*

1779

Aromatic nucleophilic substitution reactions of
2-chloro-1-methylpyridinium iodide with phenols

IPC: Int. Cl.⁷ C 07 C 39/04

The kinetics and mechanism of nucleophilic substitution reactions of 2-chloro-1-methylpyridinium iodide with different phenols have been investigated. The reactions follow second-order kinetics with a two-stage mechanism.

Mahbub Kabir*, Abdul Awwal, Delwar Hossain & Nasima K Bizly

1782

An improved synthesis of homoisoflavanones

IPC: Int.Cl.⁷ C 07 D 311/38

An improved one pot synthesis of homoisoflavanones has been carried out from 2′-hydroxydihyrochalcones.

Sharda Jaspal* & S K Grover

1784

Microwave assisted synthesis of some new isoxazolyltriazinan-2-ones

IPC: Int.Cl.⁷ C 07 D 261/00, 251/00

Trimolecular condensation of N-(5-methyl-3-iso­xazolyl)-N¢-aryl ureas 2 with aqueous formaldehyde and primary amines under microwave irradiation in ethanol leads to 5-alkyl-1-(5-methylisoxazol-3-yl)-3-aryl-[1,3,5]triazinan-2-ones 3 in excellent yields.

E Rajanarendar*, K Ramu & M Srinivas

1787

Hydrazinium monoformate mediated facile preparation of amines from azides catalyzed by zinc

IPC: Int.Cl.⁷ C 07 C 211/00

R-N₃  R-NH₂

R= alkyl or aryl

H S Prasad, G R Srinivasa, K Abiraj &

D Channe Gowda*

Synthesis of 2-oxo-2H-chromene-3-carboxylic acid (5-methyl-3-isoxazolyl) and (3-methyl-5-styryl-4-isoxazolyl) amides as potential bioactive compounds

IPC: Int.Cl.⁷ C 07 D 311/00

Synthesis of 2-oxo-2H-chromene-3-carboxylic acid (5-methyl-3-isoxazolyl) and (3-methyl-5-styryl-4-isoxazolyl)amides 3 and 6 has been achieved from aminoisoxazoles, by treatment with diethyl malonoate followed by cyclization with salicylaldehydes.

Scope of mercuric acetate oxidation of chalcones and the antibacterial activity of resulting aurones

IPC: Int.Cl.⁷ C 01 G 13/00 // A 61 P 31/04

Mercuric acetate oxidation in DMSO of some highly substituted hydroxychalcones has been studied and found to give around 50% yields of Z-aurones. Thirteen new aurones have been synthesised from the corresponding o-hydroxychalcones. These compounds have been studied for their antibacterial activity

Synthesis and insecticidal activity of some 1,3,4-oxadiazole derivatives containing phenoxy­fluoro­phenyl group

IPC: Int.Cl.⁷ C 07 D 271/10

The possibility of generation of insecticidal activity in oxadiazoles by the substitution of phenoxyfluoro-phenyl group is attempted. Synthesis and data on insecticidal activity of some new 1,3,4-oxadiazole derivatives are reported.

Bacopasaponin H: A pseudojujubogenin glycoside from Bacopa monniera

IPC: Int.Cl.⁷ A 61 K 35/00

A new dammarane-type pseudojujubogenin glycoside, bacopasaponin H, has been isolated from Bacopa monniera

Bacopasaponin H (1)

Premnosidic acid, a new iridoid glycoside from Premna barbata

IPC: Int.Cl.⁷ C 07 D 311/00

A new iridoid glycoside, premnosidic acid 1 has been isolated from P. barbata and characterized.

A new isoflavone from Indigofera linnaei

IPC: Int.Cl.⁷ C 07 D 311/36

A new isoflavone characterized as 7,8-methylenedioxy-4¢-methoxyisoflavone by chemical and spectral studies, has been isolated from the whole plant of Indigofera linnaei.