Indian Journal of Chemistry

	Papers
1 OC 185	Synthesis and characterization of {[(n-Bu)₂Sn(O₂CCH=CHAr)]₂O}₂ and crystal structure of {[(n-Bu)₂Sn(O₂CCH=CHPh)]₂O}₂ IPC: Int.Cl.⁷ C 07 C 133/20	Ten organotin compounds {[(n-Bu)₂Sn (O₂CCH = CHAr)]₂O}₂ have been synthesized by the reaction of (n-Bu)₂SnO with ArCH=CHCO₂H in 1:1 molar ratio. The crystal structure of {[(n-Bu)₂ Sn(O₂CCH = CHPh)]₂O}₂ is determined by X-ray single crystal diffraction.

	*Handong Yin, Chuanhua Wang & Chunlin Ma**
2 OC 337	Synthesis of some novel spiro heterocycles IPC: Int.Cl.⁷ C 07 D 239/00	A new class of spiro pyrimidinetriones, thioxopyrimidinediones, pyrazolidi-nediones and isoxazoline-diones are prepared from dihydropyridine/ pyran/thiopyran dicarboxylates.

	*V Padmavathi, B Jagan Mohan Reddy, A Padmaja, K Venugopal Reddy & M Rajagopala Sarma**
3 OC 217	Synthesis and mesomorphic behaviour of 3-[4-alkyloxyphenyl]-5-[3, 4-ethylenedioxybenzyl]-2-isoxazolines IPC: Int.Cl.⁷ C 07	A simple homologous series of 3-[4-alkyloxyphenyl]-5-[3,4-methylenedioxybenzyl]-2-isoxazolines having chiral sources have been synthesized by the reaction of aldoximes with safrole using chloramine-T. The synthesized compounds exhibit chiral nematic phase (N), smectic A (SA) and chiral smectic phases (SC).

	*K B Umesha, K M L Rai, Nagappa & J Mahadeva**
4 OC 339	Efficient synthesis of 1,2,4-triazolo[4,3-a][1,8]naphthyridines using nitrous acid under microwave irradiation IPC: Int.Cl.⁷ C 07	A simple and efficient protocol for the synthesis of 1,2,4-triazolo[4,3-a][1,8]naphthyridines using nitrous acid under microwave irradiation is described.

	*K Mogilaiah, M Prashanthi & K Vidya\**
5 OC 089	Microwave induced synthesis of 3/4-substituted- 2-thioxo-/2-oxo-6-thioxo-1,2,3,4,6,7 hexahydrothia zolo [4, 5-d] pyrimidine and thiazole derivatives IPC: Int.Cl.⁷ C 07 D 239/00, 277/00	3/4-Substituted-2-oxo-6-thioxo-1,2,3,4,6,7 hexa hydrothiazolo[4,5-d] pyrimidine derivatives 3, 3/4-substituted-2, 6-dithioxo-1, 2, 3, 4,6,7-hexahydrothiazolo[4,5-d]pyrimidine 4 and 4,5-substituted thiazole derivatives 6 have been synthesized by using MW irradiation technique, which gives better yield than the conventional method.

	*Vijay V Dabholkar & Syed Sagir Ahmed**
6 OC 261	Microwave accelerated Pechmann synthesis of new isoxazolyl coumarins in dry media IPC: Int.Cl.⁷ C 07 D 311/00	A fast and efficient synthesis of isoxazolyl coumarins 2 has been performed via the Pechmann reaction by microwave irradiation on solid support, montmorillonite K-10, which also acts as lewis acid catalyst. New isoxazolyl coumarins have been prepared for the first time under dry conditions using microwave and by conventional method.

	*E Rajanarendar, P Ramesh & K Ramu**
7 OC 275	Synthesis, characterization and electrochemical behaviour of some substituted 2-phenyl-4-(4¢-arylazophenyl)-3-thioxo-2H,3,4-dihydro-2,4,9,10-tetraazaphenanthren-1-ones IPC: Int.Cl.⁷ C 07 D 221/10	The electrochemical reduction of some substituted 2-phenyl-4-(4¢-arylazophenyl)-3-thioxo 2H-3, 4¢-dihydro-2, 4, 9, 10-tetraazaphenan threne-1-ones has been studied over wide pH range.The kinetic parameters have also been studied.
	R = (a) H, (b) 4¢-Cl, (c) 4¢-OH, (d) 3¢- C₂H₅
	*Pratibha Sharma, Ashok Kumar, Manisha Sharma & Siya Upadhyay**
8 OC 396	Porcine pancreas lipase catalysed acetylation of b-cyclodextrin anchored 4-t-butylcyclohexanol IPC: Int.Cl.⁷ C 07 C 13/18	Porcine pancreas lipase catalyzed acetylation of 4-t-butylcyclohexanol anchored inside b-cyclodextrin cavity gives the highest yield of 86.6% with variation in trans/cis ratio.

	Balaraman Manohara & Soundar Divakar*
9 OC 191	Benzopyrans: Part 47– Reactions of 3-(b-dimethylaminoacryloyl)-1-benzopyran-4-one with some nitrogen nucleophiles IPC: Int.Cl.⁷ C 07 P 311/04	The title pyranone 1 gives a mixture of pyridines 4 and 7 with ammonia, pyridine 5 and pyrazole 10 with phenylhydrazine, and pyridine N-oxide 8 with hydroxylamine.

	*Chandra Kanta Ghosh, Sumit Kumar Karak & Amarendra Patra**
10 OC 409	Synthetic and biological activity evaluation studies on novel isoxazolidines IPC: Int.Cl.⁷ C 07 D 261/64 // A 61 P 31/04	A series of isoxazolidines have been prepared. Some of these compounds exhibit antioxidant and antibacterial activities. Enantioselective deacetylation studies on isoxazolidines using Candida rugosa lipase are also described.

	Shubhasish Mukherjee, Raunak, Ashish Dhawan, Poonam, Ashok K Prasad, Carl E Olsen, Ashok L Cholli, William Errington, Hanumantharao G Raj, Arthur C Watterson & Virinder S Parmar*
11 OC 159	Studies on stereoselective synthesis of ethyl anti-4-substituted phenyl-2-oxo-1,3-oxazolidine-5-carboxylates and their anti-bacterial activity IPC: Int.Cl.⁷ C 07 D 263/00 // A 61 P 31/04	Ethyl anti-4-substituted phenyl-2-oxo-1,3-oxazolidine-5-carboxylates have been synthesized stereoselectively from N-Boc-b-amino alcohols by O-tosylation followed by S_N2 cyclization. All the compounds prepared are tested for their in vitro anti-bacterial activity against S. aureous, E.faecalis and E.faecium.

	*G Madhusudhan, G Om Reddy, J Ramanatham & P K Dubey**
12 OC 153	Potential plant growth regulators: Synthesis and activity of new substituted N-(2-benzoyl-4-chlorophenyl)benzamides and N-[4-chloro-2-(a,a-hydroxyphenylmethyl)phenyl]benzamides IPC: Int.Cl.⁷ C 07 C 233/07

	Jaywant Govind Hatim & Vidya Joshi*
13 OC 174	¹H NMR spectral studies of some 2,6-diaryl-4-aminothianes IPC: Int.Cl.⁷ C 07 D 335/02	¹H NMR spectra have been recorded for 4-amino-r(2),t(6)-diphenylthiane 5 and epimeric 4-aminothianes 6a-8a and 6b-8b and analysed.

	*K Pandiarajan & A Manimekalai**
	Notes
14 SCCB 164	Synthesis of pyrazoline and isoxazoline in triethanolamine medium IPC: Int.Cl.⁷ C 07	Reactions of chalcones 1a-u with phenylhydrazine and hydrazine hydrate give pyrazolines 2a-u and with hydroxylamine hydrochloride yield isoxazolines 3a-c in triethanolamine medium.

	*Nitin N Agrawal & P A Soni**
15 SCCB 081	Synthesis of 2-(coumarin-3-yl)-4-(chromon-3-yl)-benzopyrano[4,3-b]pyridines IPC: Int.Cl.⁷ C 07 D 311/00	A series of new 2-(coumarin-3-yl)-4-(chromon-3-yl)benzopyrano[4,3-b]pyridines 3a-l have been prepared from coumarinoylmethylpyridinium bromide 1 under Kröenke’s conditions.

	*G Jagath Reddy, C Thirupathaiah, D Latha, K Srinivasa Rao & Md Khalilullah**
16 SCCB 101	A new route for the convenient synthesis of 3-aminomethyl-3,5,5-trimethyl-cyclohexanol IPC: Int.Cl.⁷ C 07 C 13/18, 35/00	A new convenient route for the synthesis of 3- aminomethyl-3,5,5-trimethyl-cyclohexanol 5 and for two new intermediates 1,3,3-trimethyl-5-oxo-cyclohexane-carboxylic acid amide 3 and 5-hydroxy-1,3,3-trimethyl-cyclohexane-carboxylic acid amide 4, has been reported. Compound 5 has been identified as an important inhibitor of influenza virus fusion derivative and a potent and effective surrogate for the quinolizidine moiety.
	1 5
	*Satish C Pandey, Sudhir S Singh, Balaram Patro & Anil C Ghosh**
17 6944	A rapid and efficient synthesis of β-casomorphin employing Boc-amino acids and 9-fluorenylmethyl chloroformate as a coupling agent IPC: Int.Cl.⁷ C 07	Synthesis of β-casomorphin H-Tyr-Pro-Phe-Pro-Gly-OH employing Boc-amino acids and Fmoc-Cl as a coupling agent for peptide bond formation is described. The method is simple, efficient and rapid.

	*V V Suresh Babu & S J Tantry**
18 SCCB 175	A convenient synthesis of 1,2,4-triazolo[4,3-a][1,8]naphthyridines under solventless microwave irradiation IPC: Int.Cl.⁷ C 07 D 401/00, 249/24	A simple and efficient method for the synthesis of 4-aryl-1-(2-pyridyl)-1, 2, 4-triazolo[4, 3-a][1,8]-naphthyridines using iodobenzene diacetate (IBD) under microwave irradiation is described.

	*K Mogilaiah, S Kavitha & G Rama Sudhakar**
19 SCCB 069	Microwave-assisted rapid synthesis of thiosemicarbazide derivatives IPC: Int.Cl.⁷ C 07 C 337/06	Rapid and highly efficient synthesis of thiosemicarbazides by the coupling of isothiocyanate and carboxylic acid hydrazides in small amount of a polar solvent has been achieved under microwave irradiation by using a domestic microwave oven. The reaction proceeds rapidly, and is completed within 2-4 minutes giving a series of thiosemicarbazide derivatives 4-5(a-c) in high yields. All the compounds are fully characterized by FT-IR, 1H NMR, and mass spectroscopy.

	*Khosrow Zamani, Khalil Faghihi, Shirindokht Bagheri & Mahdi Kalhor**
20 SCCB 177	Unusual migrations and cyclization in the preparation of b-azido alcohols from b-hydroxy esters IPC: Int.Cl.⁷ C 07 D 317/00	Migration of TBDMS and Boc groups from 2° alcohols to 1° alcohols during the reduction of b-hydroxy esters has been observed. Also, unusual cyclization has been noticed during tosylation of benzylic alcohol in tert-butyl((2R)-2-hydroxy-2-phenylethyl)carbonate with S_N2 inversion.

	*G Madhusudhan, G Om Reddy, J Ramanatham & P K Dubey**
21 SCB 115	Synthesis and antimicrobial screening of certain novel Mannich bases bearing 1,8-naphthyridine moiety IPC: Int.Cl.⁷ C 07 D 401/00 // A 61 P 31/04	A series of novel Mannich bases 4 have been prepared from (2-oxo-3-phenyl-2H-[1,8]naphthyridin-1-yl)acetic acid hydrazide 1 and screened for their antibacterial activity.

	*K Mogilaiah & B Sakram**
22 SCCB 159	Synthesis and antimicrobial screening of 2,4-diaryl-6-[2¢H-[1¢]-4¢-hydroxy-2¢-oxo-benzopyran-3¢-yl]pyridines and 2,6-diaryl-4-[2¢H-[1¢]-4¢-hydroxy-2¢-oxo-benzopyran-3¢-yl]pyridines IPC: Int.Cl.⁷ C 07 D 213/00 // A 61 P 31/04	A facile synthesis of 2,4-diaryl-6-[2¢H-[1¢]-4¢-hydroxy-2¢-oxo-benzopyran-3¢-yl]pyridine and 2,6-diaryl-4-[2¢H-[1¢]-4¢-hydroxy-2¢-oxo benzo-pyran-3¢-yl]pyridines.

	*V V Mulwad & D S Satwe**
23 SCCB 139	*New biologically active constituents from Terminalia chebula* stem bark IPC: Int**.Cl.⁷ A 61 K 35/78 // C 07 D 311/32	Evidences are presented for the isolation and structures of two new compounds namely, 5, 7, 2'-tri-O-methylflavanone-4'-O-b- d-galactopyranosyl-(1 ® 3)-b-d-glucopyranoside 1 and 2a, 19a-dihydroxy-3-oxo-12-en-28-oic acid-28-oic acid-O- a -l-rhamnopyranosyl-(1 ® 4)-b-d-glucopyranoside 2 from the bark of Terminalia chebula which are obtained along with known substances b-amyrin, lupeol and friedelin. Compound 1 displays antifungal activity while compound 2 exhibits both antifungal and antifeedant activities.

	*S K Srivastava & S D Srivastava**
24 OC 241	*A new sesquiterpene lactone from Artemisia annua* leaves IPC: Int**.Cl.⁷ C 07 A 61 K 31/00	A new rearranged farnesyloxy sesquiterpene lactone 1 has been isolated from the leaves of Artemesia annua. The structure of this compound has been established as 5α-[3¢ (15¢),7¢ (14¢),11¢ (13¢)-trien]pentadecenyloxydihydrorteannuin B(1) on the basis of its spectral analysis.

	Tarun Singh & R S Bhakuni*

Indian Journal of Chemistry

Notes