Indian Journal of Chemistry

Sect. B: Organic Chemistry including Medicinal Chemistry

Total visitors:2,694 since 18-02-07

VOL. 46B

NUMBER 3

MARCH 2007

CONTENTS

Papers

 

 

 

471

HPAEC and MALDI-TOF-MS analysis of oligo­saccharides generated from sesame meal by enzy­matic hydrolysis

 

IPC: Int.Cl.8 C07C

Generation of xyloglucan oligosaccharides 1 through 6 from Sesamum indicum meal by enzyme hydrolysis and their characterisation by sugar compositional and linkage analysis, HPEAE-PAD-chromatography and MALDI-TOF-mass spectrometry has been carried out.

 

 

 

 

 

 

 

Kaushik Chattopadhyay, Partha Ghosh, Pradyot Ghosal & Bimalendu Ray*

 

 

 

 

 

 

 

 

 

 

 

 

 

478

Prediction of acidity constant for substituted acetic acids in water using artificial neural networks

 

IPC: Int.Cl.8 C07C

Linear and non-linear quantitative structure-activity relationships have been successfully developed for the modeling and prediction acidity constant (pKa) of 87 substituted acetic acids with diverse chemical structures.

 

 

 

 

Aziz Habibi-Yangjeh* &

Mohammad Danandeh-Jenagharad

 

 

 

 

 

 

 

 

488

Synthesis of 1-alkyl/aralkyl-2-(1-arylsul fonylalkyl)­benzimidazoles under PTC conditions

 

 

IPC: Int.Cl.8 C07D

 

2-(α-Chloroalkyl)benzimidazoles 1 on reaction with arylsulphinate sodium salt 2 in CH3CN under PTC conditions, give 3 which on alkylation yields 1-alkyl/aralkyl 2-(α-arylsulfonylalkyl)benzimidazoles 4. Alternatively, 4 can also be prepared by the reaction of 2 with 1-alkyl/aralkyl-2-(α-chloroalkyl)­benzi­mida­zole 5 in CH3CN using PTC conditions.

 

 

 

 

 

 

 

P K Dubey*, P V V Prasada Reddy & K Srinivas

 

 

 

 

 

 

 

 

 

 

 

 

 

492

Chemical constituents of Evolvulus nummularius

 

IPC: Int.Cl.8 C07C

 

Three new compounds 1-3 along with β-sitosterol and its glucoside, stigmasterol, d-mannitol, ursolic acid and oleanolic acid have been isolated from aerial parts of Evolvulus nummularius (Convolvulaceae).

 

 

 

1 R΄= stearoyl, R= stigmasteryl

 

 

2

 

 

3s

 

 

 

Biswanath Dinda*, Biplab Ghosh, Shiho Arima, Nariko Sato & Yoshihiro Harigaya

 

 

 

 

 

 

 

 

499

Novel one-pot synthesis of 1,3-dithiins and 1,3-thiazines under microwave irradiation

 

IPC: Int.Cl.8 C07D

Microwave induced synthesis of 1,3-dithiins and 1,3-thiazines involving Knoevenagel condensation followed by Michael addition under solvent-free conditions in one-pot is reported. The reaction is catalyzed by cheap and easily available NaCl.

 

 

 

 

 

 

 

Ibadur R Siddiqui* & Pravin K Singh

 

 

 

 

 

 

 

 

 

 

 

 

 

505

Synthesis of CL-20: By oxidative debenzylation with cerium(IV) ammonium nitrate (CAN)

 

IPC: Int.Cl.8 C07D

 

A simple debenzylation approach has been discussed for the synthesis of hexanitrohexaazaisowurtzitane (HNIW or CL-20) one of the most powerful high explosives of today with cerium ammonium (IV) nitrate.

 

 

 

 

 

G M Gore, R Sivabalan*, U R Nair, A Saikia,

S Venugopalan & B R Gandhe

 

 

 

 

 

 

 

509

p-Selectivities of trans-2-heterobicyclo­[4.4.0]­decan-5-ones in reductions with NaBH4 and Na(CN)BH3

 

IPC: Int.Cl.8 C07D

The nheteroatoms*# interaction hypothesis to explain the relative reaction rates and the axial selectivities of nucleophilic additions to 2-hetero­bicyclo[4.4.0]­decan-5-ones in relation to the corresponding carba-analog does not find experimental as well as theoretical support. The selectivity is rather dependent on the differential electron-withdrawing abilities of the heteroatoms that translate further into differential svicinalp*C=O interactions in the ground states of the molecules. The heightened axial selectivity of the aza-species is probably due to hydrogen bonding of nitrogen with the solvent that enhances its electron withdrawing ability further.

 

 

 

 

 

 

Rengarajan Balamurugan,

Vardhineedi Sriramurthy & Veejendra K Yadav*

 

 

 

 

 

 

 

 

 

 

 

 

 

516

Orizalanasteroloide A and B from rice hulls of Oryza sativa

 

IPC: Int.Cl.7 C07C

Two new triterpene glycosides have been reported from Oryza sativa and structure elucidated by spectroscopic methods.

 

 

 

 

 

 

 

Ill-Min Chung, Mohd Ali & Ateeque Ahmad*

 

 

 

 

 

Notes

 

 

 

523

Synthesis and spectrum of new Schiff bases as polydentate ligands and potential antibacterial reagents

 

IPC: Int.Cl.7 C07D

Eight novel linear polydentate Schiff base ligands, N,N′-bis(R-iminoethyl)-2,6-pyridine- dicarboxylic diamide IIa-g, have been synthesized. Micro­calorimetric test of the inhibitory capacities of these compounds on E. coli and S. aureus show that they have antibacterial activity to different extent.

 

 

Li-Hua Cai, Pei-Zhi Hu *, Xiao-Lan Du,

Li-Xia Zhang & Yi Liu

 

 

 

 

 

 

 

529

Lewis acid catalyzed amino-Claisen rearrange­ment: A facile one pot synthesis of 2-allylaryl­amines from N-allylarylamines

 

IPC: Int.Cl.8 C07C

 

Boron trifluoride-diethyl ether complex efficiently catalyzes a variety of amino-Claisen rearrangement of N-allylarylamines 1a-g to afford 2-allylarylamines
2a-g in moderate to good yields.

 

 

 

 

 

 

Seema Jain, Neelesh Pandey & D Kishore*

 

 

 

 

 

 

 

 

 

 

 

 

 

532

Synthesis of pyrazole and isoxazole in tri­ethanol­amine medium

 

IPC: Int.Cl.8 C07D

Reaction of 2'-hydroxy chalcone dibromides with phenyl hydrazine and hydrazine hydrate affords pyrazoles and with hydroxylamine hydrochloride give isoxazoles in triethanolamine medium. Similarly reaction of b-diketone with phenyl hydrazine and hydrazine hydrate in TEA gives pyrazoles in high yield in shorter time.

 

 

 

 

 

 

 

 

 

 

Nitin N Agrawal* & P A Soni

 

 

 

 

 

 

 

535

Enamination of 1,3-dicarbonyl compounds catalyzed by tin tetrachloride

 

IPC: Int.Cl.8 C07C

Tin tetrachloride has been found to be an extremely efficient catalyst for the enamination of 1,3-dicarbonyl compounds under solvent-free conditions at room temperature.

 

 

 

 

 

 

 

 

Zhan-Hui Zhang*, Zi-Chuan Ma & Li-Ping Mo

 

 

 

 

 

 

 

 

 

 

 

 

 

540

Reaction of 2-acetylbenzofuranhydrazone with aromatic aldehydes: Formation of aldzaines and regeneration of 2-acetylbenzofuran

 

IPC: Int.Cl.8 C07D

Hydrolytic cleavage of 2-acetylbezofuran hydrazone under acidic condition with aromatic aldehyde is described.

 

 

 

 

Ravi K Ujjinamatada* &

Yankangouda S Agasimundin

 

 

 

 

 

 

 

544

Synthesis and bioactivity study of 2,5-bismer­capto-1,3,4-thiadiazole heterocyclic derivatives

 

IPC: Int.Cl.8 C07D

A series of acylhydrazone compounds 3 and acylthiosemicarbazides 4 and some heterocyclic derivatives 5 containing thiadiazole rings have been synthesized conveniently in high yields. The bioassay result indicates that some compounds have relatively low antibacterial activity and bioactivity for improving plant growth.

 

 

 

 

 

 

Man-Lin Li, You-Ming Zhang & Tai-Bao Wei*

 

 

 

 

 

 

 

 

 

 

 

 

 

550

Synthesis and characterization of new quin­azolines as potential antimicrobial agents

 

IPC: Int.Cl.8 C07D

Several Aryl-N-(5-{4-[2-(2-chlorophenyl)-4-oxo(3-hydro­quinazolin-3-yl)]phenyl} (1,3,4,thiadiazol-2-yl))­amides 4a-l have been prepared and tested for their antibacterial and antifungal activities.

 

 

 
R= 2-Chlorophenyl, Ar = different aryl groups

 

 

N C Desai*, P N Shihora & D L Moradia

 

 

 

 

 

Authors for correspondence are indicated by (*)

IPC: International Patent Classification

Int.Cl8.: International Classification, 8th Edition, 2006