Indian Journal of Chemistry
Sect. B: Organic Chemistry including Medicinal Chemistry Total visitors: 3,563  since 23-01-09
VOL. 48B		NUMBER 1		January 2009
CONTENTS
Papers
83	New antifungal triterpenoid saponin from Launaea pinnatifida Cass.		A new antifungal triterpenoid saponin (compound 1) 3β-O-[α-L-rhamnopyranosyl-(1→3)-O-α-L-arabinopyranosyl-(1→3)-O-β-D-galactopyranosyl]-spergulatriol along with known compounds glutenol and hopenol-b has been isolated from the methanol soluble fraction of the defatted seeds of the plant.
	R N Yadava* & N Chakravarti
88	Synthesis and in vitro study of biological activity of heterocyclic N-Mannich bases		Three series of N-Mannich bases of 3,4-dihydropyrimidine-2(1H)-ones (DHPMs) 7a-g, 8a-g and 9a-g have been prepared by Mannich reaction of three DHPMs derivatives 4a, 4b and 4c respectively with seven different heterocyclic secondary amino compounds 6a-g and formaldehyde 5. All the three series of N-Mannich bases have been analyzed with a view to elucidate their elemental analysis and spectral studies (FTIR, ^1H NMR). They have been assayed in vitro for their antimicrobial activity.
	T B Shah*, A Gupte, M R Patel, V S Chaudhari, H Patel & V C Patel
97	Substituted 1,2,4-triazoles and thiazolidinones from fatty acids: Spectral characterization and antimicrobial activity		Fatty hydrazides are reacted with phenyl isothiocynate to give thiosemicarbazides followed by cyclization to furnish 1,2,4-triazoles and thiazolidinones in moderate yield.
	Mudasir Rashid Banday & Abdul Rauf *
103	Conformational studies of nonapeptide using NMR		The study of conformation of nonapeptide Tyr-Met-Asp-Gly-Thr-Met-Ser-Gln-Val (YMDGTMSQV), capable of being recognized by melanoma specific T-cells, corresponds to residue 369 to 377 of tyrosenase gene has been carried out. Secondary structures have been obtained by ^1H NMR and molecular dynamic simulation using CSI values, 2D COSY, NOESY and ROESY.
	Jalaj Tripathi*, Prashant Desai, Sudha Srivastava & Evans Cuthino
110	Conformational study of N‑acyl‑r-2‑c-4‑diphenyl‑3‑ azabicyclo[3.3.1]nonanes and N3,N7‑diformyl‑r-2,c-4,t-6,t-8‑tetraphenyl‑3,7-diazabicyclo[3.3.1]nonane by NMR spectroscopy and semi-empirical molecular orbital calculations		The stereochemistry and stereodynamics of N‑chloroacetyl‑ and N‑benzoyl-r‑2,c‑4‑ diphenyl‑3‑azabicyclo[3.3.1]nonanes and N3,N7‑diformyl‑r‑2,c‑4,t‑6,t‑8-tetraphenyl‑ 3,7‑diazabicyclo-[3.3.1]nonane have been studied using NMR spectral techniques and semi-empirical calculations.
	M Venkatraj*, S Ponnuswamy & R Jeyaraman
Notes
120	H3PW12O40 catalyzed efficient synthesis of 4-substituted coumarins
	B China Raju*,T Hari Babu & J Madhusudana Rao
124	Synthesis and plant growth regulatory activity of o-nitrobenzoylthiourea derivatives		A series of o-nitrobenzoylthiourea derivatives have been synthesized in high yields. Some of the compounds have considerable wheat growth promoting activities.
	Qi Lin, Hong Yao, Tai-Bao Wei & You-Ming Zhang*
128	Synthesis and antimicrobial screening of 4H-2-benzoyl-3-hydroxy-3-methyl-2-phenyl 2,3-dihydro-furo[3,2-c]benzopyran-4-one and 4H-3-methyl-2-phenyl furo[3,2-c]benzopyran-4-one		A facile synthesis of biologically active 4H- 2-benzoyl-3-hydroxy-3-methyl-2-phenyl 2,3-dihydro-furo[3,2-c]benzo-pyran-4-one and 4H-3-methyl-2-phenylfuro[3,2-c]benzo-pyran-4-one from 3-acetyl-4-hydroxy 2H[1]benzopyran 2-one through acid catalysed 1,2-elimination is presented.
	V V Mulwad* & A S Hegde
134	Tungstate-catalysed oxidation of triptans with hydrogen peroxide: A novel method for the synthesis of N,N-dimethyltryptamine N-oxides		Synthetic method of important metabolites N,N-dimethyl-2-[5-[substituted-1H-indole-3-yl]ethanamine-N-oxides 8a-d of triptans 1-4 and their spectral data is reported.
	Purna Chandra Ray*, Vasantha Mittapelli, Yogendra Kumar Chauhan, Babu Rao Konudula & Om Dutt Tyagi
137	Synthesis and antimicrobial screening of 5-benzylidine-2-imino-3-(2-oxo-2H-benzopyran-6-yl)-thiazolidin-4-one and its derivatives
	Vinata V Mulwad* , Abid Ali Mir & Hitesh T Parmar
142	Synthesis of Schiff’s bases of 8-methyltetra-zolo[1,5-a]quinoline as potential anti-inflam-matory and antimicrobial agents
	Sandhya Bawa* & Suresh Kumar
146	Synthesis of functionalized diaryl alkanes from azines		Substituted diaryl alkanes are synthesized from benzalazines and acetophenone/propiophenone azines via Friedel Craft`s reaction with substituted mono- and poly-nuclear aromatic hydrocarbons. Diaryl methanes/ethanes and propanes are obtained by reaction with benzalazine, N,N'-bis(1-phenyl) azine and N,N'-bis(1-propyl)azine, respectively.
	Rudolf M Manih & Bekington Myrboh*
152	A one pot method of conversion of aldehydes into nitriles using iodine in ammonia water: Synthesis of 2-chloro-3-cyanoquinolines		One pot rapid transformations of heteroaromatic carbaldehyde to cyano group by using cheap and easily available iodine and ammonia water has been described.
	Shraddha Upadhyay, Atish Chandra & R M Singh*
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