Indian Journal of Chemistry
Sect. B: Organic Chemistry including Medicinal Chemistry Website address: www.niscair.res.in; nopr.niscair.res.in Total visitors: 1,497  since 03-07-09
VOL. 48B		NUMBER 7		July 2009
CONTENTS
Papers
981	HOAt.DCHA as co-coupling agent in the synthesis of peptides employing Fmoc-amino acid chlorides as coupling agents: Application to the synthesis of β-casomorphin		Racemization free protocol for the synthesis of peptides employing Fmoc-amino acid chlorides mediated by HOAt.DCHA as co-coupling agent has been described.
	Vommina V Sureshbabu* & Gundala Chennakrishnareddy Peptide Research Laboratory, Department of Studies in Chemistry, Central College Campus, Dr. B. R. Ambedkar Veedhi, Bangalore University, Bangalore 560 001, India
989	Synthetic studies towards steroid-amino acid hybrids
	Shagufta, Ritesh Singh & Gautam Panda* Medicinal and Process Chemistry Division, Central Drug Research Institute, Mahatma Gandhi Marg, Lucknow 226 001, India
996	Synthesis of novel benzothiozole and benzisoxazole functionalized unsymmetrical alkanes and study of their antimicrobial activity		Synthesis of novel benzothiozole and benzisoxazole functionalized unsymmetrical alkanes is achieved and their antibacterial and antifungal activity studied.
	Ravindra M Kumbhare* & V N Ingle Fluoroorganic Division, Indian Institute of Chemical Technology, Hyderabad 500 007, India
1001	Facile one-pot synthesis of new annulated hexacyclic ring system indeno-pyrano-furo-indoles and spiro indenopyran-indoles under microwave irradiation		Facile efficient synthesis of fused and spiro indole derivatives under microwaves is reported.
	Anshu Dandia*, Ruby Singh & Dharmendra Singh Department of Chemistry, University of Rajasthan, Jaipur 302 004, India
1006	Synthesis and pharmacological studies of some phthalimidoxy substituted spiro-thiazolidinone derivatives of isatin		Some 3'-{4-(1-acetyl-5-(4-substituted phenyl)-2-pyrazoline-3-yl)phenyl}-1-N-ethoxyphthalimido-4'H-spiro[indole-3,2'-[1,3]thiazolidene]-2,4'-1H-diones 6a-e have been synthesized from 3-[4-{1-acetyl-5-(4-substitutedphenyl)-2-pyrazoline-3-yl}phenylimino]indole-2-one 4a-e. Synthesized compounds have been characterized by analytical and spectral studies.
	Dinesh Bhambi, Chirag Sharma, Shweta Sharma, Vijay Kumar Salvi & G L Talesara* Synthetic Organic Chemistry Research Laboratory Department of Chemistry, M.L. Sukhadia University, Udaipur 313 001, Rajasthan, India
	Notes
1013	A new versatile strategy for design and synthesis of reduced risk fungicides: Bibenzyl core incorporated with modified as-indacene		A novel montmorillonite K 10 clay catalyzed Michael addition followed by dehydrative cyclization in one-pot is designed to synthesize 4,4'-bis(4",8"-aryl-1",4"-dihydro-bisthiazolo[3,2-a;5'",4'"-e]pyrimidine-2"-thion-1"-yl)bibenzyls 6a-j with excellent yield under microwave irradiation in solvent-free conditions. Antifungal screening results on Fusarium oxysporum and Penicillium citrinum show that most of the synthesized compounds display promising antifungal activity.
	Pravin K Singh* & Ibadur R Siddiqui Laboratory of Green Technology, Department of Chemistry, University of Allahabad, Allahabad 211 002, India
1019	An iridoid with anticancer activity from the sepals of Mussaenda ‘dona aurora’		A new cytotoxic iridoid glycoside and a number of known flavonols and iridoids have been reported.
	K S Vidyalakshmi* & G V Rajamanickam Department of Chemistry, PRIST University, Thanjavur, Tamilnadu, India
1023	Chromium(III) chloride catalyzed one-pot synthesis of pyrimidine-2-thiones from arylidines and thioureas
	Nimalini D Moirangthem & Warjeet S Laitonjam* Department of Chemistry, Manipur University, Canchipur 795 003, Manipur, India
1027	Synthesis and characterization of fused and spiro heterocycles by ultrasonic methods		Treatment of 1,4-diazacyclohexan-2,5-dione 1 with bromine in carbontetrachloride yielded 1,4-diaza-3-bromo-2,5-dioxocyclohexane 2 and 1,4-diaza-3,3-dibromocyclohexane-2,5-dione 7. The reaction of 2 with carbamides/thiocarbamides produced 6-oxo-oxazolo[4,5-b] piperazine 5 /2-substituted imino-6-oxo-thiazolo[4,5-b] piperazine 6. Compound 7 on combination with carbamides/ thiocarbamides was transformed to 1-oxo-2-substituted imino-3,5,8-triaza-3H,5H,8H,7-dihydro-6,9-dioxo-spiro [3.5] nonane 9 and 1-thia-2-substituted imino-3,5,8-triaza-3H,5H,8H-7dihydro-6,9-dioxo-spiro [3.5] nonane 9.
	Vijay V Dabholkar* & Mihir M Wadkar Organic Research Laboratory, Department of Chemistry, K.C. College, Churchgate, Mumbai 400 020, India
1033	Synthesis and evaluation of some new substituted phenylthiazole derivatives and their antitubercular activity
	Shashikant R Pattan*, Anand A Bukitagar, Jayashri S Pattan, B P Kapadnis & S G Jadhav Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravara Nagar, Loni 413713, India
1038	Isolation and characterisation of novel esters from aerial parts of Tiliacora acuminata		Two novel esters octyl(benzoylamino)acetate and heptadeca-4-ene acetate have been isolated from the aerial parts of Tiliacora acuminata. Their structures have been elucidated by spectroscopic and chemical methods.
	S Joseph Selvaraj, I Alphonse & S John Britto* Department of Chemistry, Rapinat Herbarium, St. Joseph's College, Tiruchirappalli 620 002, India
1041	New coumarin diol from the plant, Chloroxylon swietenia DC		A new coumarin diol has been isolated from the chloroform fraction of the leaves of the plant, Chloroxylon swietenia DC. The structure of new compound has been established as 6-(2’, 3’-dihydroxy-3-methylbutyl)-8-prenylumbelliferone based on the spectral (UV, IR, ^1H, ^13C and 2D NMR and mass) data.
	G Venkateswara Rao*, K Sambasiva Rao, T Annamalai & T Mukhopadhyay CavinKare Research Centre, 12, Poonamalle Road, Ekkattuthangal, Chennai 600 032, India
1045	A copper sulphate catalysed synthesis of derivatives of tetra substituted pyridine		Copper sulphate has been found to be an effective catalyst in water-ethanol solvent system for the synthesis of various tetra-substituted pyridine derivatives via Michael addition of b-dicarbonyl compounds to a,b-unsaturated oximes and subsequent ring closure.
	Mazaahir Kidwai* & Priya Green Chemistry Research Laboratory, Department of Chemistry, University of Delhi, Delhi 110007, India
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