Journal of Scientific & Industrial Research

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VOLUME 66

NUMBER 3

MARCH 2007

CONTENTS

Reviews

191

Emerging trends in tuberculosis therapy — A review





Yadvendra K Agrawal, Hardik G Bhatt, Hitesh G Raval, Pratik M Oza,
Hitesh B Vaidya, Kuntal Manna & Parthajyoti Gogoi

Tuberculosis is one of the most devastating bacterial disease having high rates of morbidity and mortality. Mycobacterium tuberculosis invades the host immune system and persists in pulmonary granulomas. Review presents bacterial cell wall or envelope structure, drug targets against M. tuberculosis and novel therapeutics agents like quinolone, pyrimidine, nitroimidazopyran and oxazolidinone derivatives. This review also focuses on the newer untouched targets like immunomodulators and isocitrate lyase inhibitors, which can be further exploited.

209

SPEEK polymeric membranes for fuel cell application and their characterization: A review





























N Nishad Fathima, R Aravindhan,
D Lawrence, U Yugandhar, T S R Moorthy & B Unni Nair

Design of polymeric membranes for fuel cells application requires suitable selection and modification of polymers. This review accounts the various polymeric membranes available for use in fuel cells, advantages of sulphonation of polymers, various sulphonation methods and the characterization techniques. Presently, SPEEK finds extensive application as polymeric membrane in fuel cells. The advantages of SPEEK include good mechanical properties, thermal stability, and toughness and some conductivity depending on degree of sulphonation.

Management & Information Technology

220

Mathematical models of tool life and surface roughness for turning operation through response surface methodology









Hari Singh & Pradeep Kumar

Mathematical models of tool life and surface roughness have been developed for turning En 24 steel with titanium carbide coated tungsten carbide inserts. Response surface methodology (RSM) has been applied for developing the models in the form of multiple regression equations correlating dependent parameters, tool life and surface roughness, with cutting speed, feed rate and depth of cut, in a turning process. The second order response surface was found suitable for present work. The central composite rotatable design was used to plan the experiment.

IPC Code: G09B25/02

227

Quantitative assessment of water consumption for manufacturing packaged drinking water at Rail Neer Plant –A case study







Brajesh K Shrivastava & Masood Alam

Case study is based on total production and cumulative water consumption of various water treatment units used in water treatment at Rail Neer Plant, Nangloi, Delhi to meet Bureau of Indian Standards specification for packaged drinking water (IS:14543: 2004) and various amendments incorporated till February 2006. The treatment system comprises of chlorination, activated carbon filtration, pesticide removing system, softener, ultrafiltration, reverse osmosis, marble chip filtration unit, micron filtration, UV disinfection and ozonation. Study was carried-out following Good Manufacturing Practices (GMP) & Good Laboratory Practices (GLP). It was found that for manufacturing one litre of Rail Neer packaged drinking water 1.64 litre water was consumed.

S & T and Industrial Research

231

Design and development of an ingenious cricket ball decorative stitching machine








 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

R W Lanjewar, G Balamurugan,
N P Mukherjee, P Saha, J Ray Chaudhury &
S S Roy

This paper presents an ingenious cricket ball decorative stitching machine, developed by CMERI, Durgapur, which provides simultaneous stitching of two parallel rows on each hemispherical leather cup of cricket ball. A unique dual needle-looper arrangement of chain stitching is developed for decorative stitching on curved surface of hemispherical leather cup. Salient design features and working principle of ball holding and indexing mechanism are discussed. Operation of motor drives, optical interrupter type sensor, and encoder are synchronized and automated by micro-controller with programmable and erasable memory. Machine tested successfully and will produce better quality cricket balls in less time than manual stitching.

S & T and Industrial Research

235

Analysis of FRP wrapped concrete columns under uniaxial compression











P Sangeetha

Fiber wrapping or encasement of columns with fiber-reinforced plastic (FRP) sheets significantly enhances strength and ductility of concrete columns. To investigate the behavior of concrete columns confined by fiber reinforced polymer (FRP) sheets under uniaxial compression, analytical models were solved using Finite Element Method (FEM) against published experimental data. Cross sections of concrete columns in the analysis are categorized into circular, square and rectangular sections. Finite Element Analysis (FEA) can effectively simulate the behavior of concrete columns confined by FRP sheets when the proper numerical model is adopted. Results from a series of the analysis on small-scale specimens showed that confinement increased strength (20-25%) and ductility of concrete columns loaded axially. ANSYS (version 6.0) offers a series of very robust nonlinear capabilities for designs and analyses.

243

Characterization of Hela cells for presentation of exogenous antigens









Mercy Devasahayam

Role of MHC class I HLA A2 HC and trimeric molecules on the binding of exogenous HBV core antigen was studied in Hela cells transfected with MHC class 1 HLA A2. HC and trimeric HLA A2 molecules could be identified with specific monoclonal antibodies. HC and trimeric HLA-A2 molecules exist in varying proportion on the cell surface of Hela cells. MHC class I HC molecules on the cell surface do not bind HBV core peptide. The exchange of peptide with MHC class 1 molecules on the cell surface is inefficient with cells exhibiting a maximal binding (12%) at 1.5mM of peptide. Hence, presentation of exogenous HBV core antigen molecules occurs after endocytosis of the antigen and MHC class 1 molecules, followed by functional trimer complex formation in endolysosomal compartments.

250

Environmentally benign synthesis of aromatic nitro compounds using silica supported inorganic nitrates

 

 

 

 

 

 

 

D M Badgujar, M B Talwar, S N Asthana &
P P Mahulikar

Simple, rapid, clean and environmentally benign synthesis of aromatic nitro compounds by using inorganic nitrates as nitrating agents adsorbed on silica gel as a solid support has been reported.

 

252

Exopolysaccharide (pullulan) production from cassava starch residue by Aureobasidium pullulans strain MTTC 1991

 

 

 

 

R C Ray & S N Moorthy

Exopolysaccharide (EPS), pullulan, production by Aureobasidium pullulans strain MTCC 1991 was evaluated using cassava starch residue (CSR), wheat bran (WB) and rice bran (RB) as solid substrates as well as carbon source, with or without amendment of basal (mineral) medium. EPS production was negligible without amendment of basal medium on all tested substrates but with the supplementation of basal medium, production of EPS was maximum on CSR (27.5 g. kg–1 substrate), followed by WB (19.5g.kg –1 substrate) and RB (2.4g.kg-1 substrate).

IPC Code: C08B11/02

Energy and Environment

256

Use of nahar oil methyl ester (NOME) in CI engines



 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Dilip Kumar Bora & Rupanjali Nath

Nahar oil methyl ester (NOME) added (up to 30%, by vol) to neat diesel can be used in the existing engine without any symptoms of undesirable combustion. This paper overviews the application of NOME in CI Engines by comparing its performance and smoke opacity with conventional diesel fuel.

IPC Code: C11B1/10

Waste Treatment and Utilization

259

Protein enrichment of pineapple waste with Saccharomyces cerevisiae by solid state bioprocessing

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Roberta Correia, Margarida Magalhães & Gorete Macêdo

Saccharomyces cerevisiae was assessed to increase protein levels of pineapple waste (PW) by solid state bioprocessing (SSB) with and without nitrogen supplementation. PW (10 g) was inoculated with S. cerevisiae. Optimum protein content (22% dry basis), which is 3.5-fold the original protein content, reached at 48 h of incubation when 0.25% (NH4)2SO4 was added to medium. Thus, fermented PW can be successfully converted into a protein-rich feed by SSB.

IPC Code: C05F9/04

 

Report

263

International symposium on advances in electrochemical science and technology
Sanjay Sengupta

Author-Reader Platform

265

Announcement

266

Instructions to contributors

 

Author Index

 



Agrawal Y K

191

Alam M

227

Aravindhan R

209

Asthana S N

250

Badgujar D M

250

Balamurugan G

231

Bhatt H G

               191

Bora D K

256

Correia R

259

Devasahayam M

243

Fathima N N

209

Gogoi P

191

Kumar P

220

Lanjewar R W

231

Lawrence D

209

Macêdo G

259

Magalhães M

259

Mahulikar P P

250

Manna K

191

Moorthy S N

252

Moorthy T S R

209

Mukherjee N P

231

Nair B U

209

Nath R

256

Oza P M

191

Raval H G

191

Ray Chaudhury J

231

Ray R C

252

Roy S S

231

Saha P

231

Sangeetha P

235

Shrivastava B K.

227

Singh H

220

Talwar M B

250

Vaidya H B

191

Yugandhar U

209



Keyword Index

 


A. pullulans

252

Antimycobacterial agents

191

B100

256

Backwashing

227

Carbide inserts

220

Cassava starch residue

252

Cell envelope

191

Chlorination

227

CI Engine

256

Composite columns

235

Core antigen

243

Cricket ball

231

Decorative stitching

231

Drugs

191

En24 steel

220

Endocytosis

243

Exopolysaccharide

252

Experimental design

220

FEM

235

Fiber wrapping

235

FRP

235

Fuel cells

209

Hela

243

Hepatitis B virus

243

Indigenous machine

231

Inorganic nitrates

250

MHC

243

MIC

191

Mycobacterium tuberculosis

191

Nahar oil

256

Nitration

250

Nitro compounds

250

Nitrogen supplementation

259

NOME

256

Permeate

227

Pineapple waste

259

Polymeric membranes

209

Protein enrichment

259

Pullulan

252

RSM

220

Saccharomyces cerevisiae

259

Silica gel

250

Solid state bioprocessing

259

Solid support

250

SPEEK

209

Surface roughness

220

Targets

191

Therapeutic agents

191

Tool life

220

Transesterification

256

Ultrafiltration

227