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Indian
Journal of Chemistry |
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Sect. B: Organic Chemistry including Medicinal Chemistry |
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VOL. 46B |
NUMBER 7 |
JULY 2007 |
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CONTENTS
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Rapid Communications
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1133 |
Photochemical studies on b-ionyl hydrazone |
Irradiation of
degassed n-heptane solution of (E,E)-β-ionone hydrazone results
in geometric isomerisation of its >C=N–linkage whereas in non-degassed
condition (E)-5,6-epoxy-b-ionone is
formed. |
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Solomon Libsu & Anil K Singh* |
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Papers
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1137 |
Towards the total synthesis of
halolitoralin-c |
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Ch Maheedhara Reddy, V N S Murthy P K Mukkanti & Palle V R Acharyulu* |
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1143 |
Simple, economical and flexible apparatus
for solid phase peptide synthesis |
Simple,
economical, flexible convenient apparatus to carry out manual solid phase
peptide/solid phase synthesis using two vessels has been designed. |
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Kota Satyanarayana*, K V R C Rajesh Kumar
& Ch Venkanna
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1148 |
Structural
feature indenture for estrogen analogs as anticancer agents: De novo
and Hansch Approach |
The quantitative
models derived for the study illustrates the significance of the b
-hydroxy group of 17th
position for the drug–enzyme interaction and allowed hydrogen-bonding
interaction to estrogenic receptor in optimal manner (free rotation) as
compared to oxo group (restricted orientation). The results of the study also reveal the necessity of sulfonamide moiety at 3rd
position of estrogen. Additionally,
presence of smaller
substituents at 2nd position will be conducive for the activity. |
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Arun Kumar Gupta*, Anurekha
Jain, Avijeet Jain, |
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1154 |
Steroidal saponins from the rhizomes of Agapanthus africanus (Linn) |
Two new spirostan saponins have
been isolated from the rhizomes of Agapanthus
africanus (Linn) and identified as (25R)-5α-spirost-7-ene-2-α,3β,5α-triol-3-O[-α-l-rhamnopyranosyl(1→2]-β-d-glucopyranoside
1 and (25R)-5α-spirost-7-ene-2α,3β,5α,9α -tetrol-3-O-β-d-glucopyranoside
2. |
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D N Singh*, N Verma & D K Kulshreshtha |
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1159 |
A selective synthesis
for novel pyranodipyrimidines |
Pyrano[2, 3-d]pyrimidines have been cyclised using various
aromatic acids on different solid supports to yield pyranodipyrimidines
selectively. |
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Mazaahir Kidwai*, Ritu Goyal & Kavita
Singhal |
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1164 |
Ester prodrugs of flurbiprofen: Synthesis,
plasma hydrolysis and gastrointestinal toxicity |
Nine alkyl ester prodrugs of flurbiprofen have been synthesized with an aim to reduce it’s gastrointestinal side-effects. |
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Rhea Mohan &
C S Ramaa* |
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1169 |
Synthesis of novel aliphatic thiourea
derivatives containing s-triazine moiety as potential antimicrobial agents |
A new series of aliphatic
thiourea incorporating 1,3,5-s-triazine moiety containing morpholine and
various substituted aryl urea is reported along with their in vitro
antimicrobial studies. |
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Akshay D Desai,
Dharmesh H Mahajan & |
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1174 |
Environmentally benign synthesis of
fluorinated pyrazolone derivatives and their antimicrobial activity |
Synthesis of
fluorinated pyrazolone derivatives from 3-formyl chromone and 4-formyl
pyrazoleby conventional,
ultrasonication and microwave irradiation has been carried out and their
antimicrobial activity has been studied. |
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S N Shelke, N R Dalvi, S B Kale, M S More, C H Gill & B K Karale* |
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1179 |
Microwave enhanced heterocyclization: A
convenient procedure for antimicrobial 1,5-benzothiazepine compounds |
A series of 2,5-di hydro- 4- [1΄-(o-chloro phenyl)-3΄-methyl-5΄-pyrazolidene azomethine]-2-(substituted phenyl)-1,5 benzothiazepines 7a-j have been synthesized using environmentally benign procedure and evaluated for their antimicrobial activity. Neat reactants are subjected to microwave irradiation (MWI) under solvent-free-condition. The observed yields and enhancement in reaction rates are due to the solvent free conditions coupled with microwave usage. Structures of the synthesized compounds have been elucidated on the basis of their elemental analyses and spectral data. |
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Krunal G Desai*
& Kishor R Desai |
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Notes
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1187 |
Rhodium chloride catalyzed facile synthesis
of α-aminonitriles |
The
facile synthesis of a series of α-aminonitriles by a one-pot
three-component condensation of carbonyl compounds, amines and TMSCN in MeCN
in presence of a catalytic amount of rhodium chloride at ambient temperature
in high yields is described. |
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M
A Pasha*, H M Nanjundaswamy &
V
P Jayashankara
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1191 |
Synthesis, spectral studies and
antimicrobial activity of
7-chloro-2-alkyl/aryl-4-alkyl/aryl-3-arylidene-3H-1,5- benzodiazepines |
Ten new
7-chloro-2-alkyl/aryl-4-alkyl/aryl-3-arylidene-3H-1,5-benzodiazepines have been synthesized and characterized as
antibacterial and antifungal agents. |
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Vijai N
Pathak*, Rahul Joshi & Neetu Gupta |
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1198 |
Study of the thermo-oxidative degradation
behavior of isotactic polypropylene with the varying ethylene content |
The thermo-oxidative degradation behaviour of isota- ctic polypropylene is studied as a function of varying ethylene and oxygen concentration effects by means of gel permeation chromatography measurements. |
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M S Alam*, S M Abdur Razzaque,
G M Arifuzzaman Khan, A
K Chakraborty &
M
Moniruzzaman
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1203 |
Microwave-assisted
solvent-free synthesis of 4-methyl-2-hydroxy- and 2-methyl-4-hydroxyquinolines |
Rapid and efficient microwave-assisted synthesis of 4-methyl-2-hydroxy- and 2-methyl-4-hydroxyquinolines from anilines and ethyl acetoacetate under different conditions is described. |
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V Nadaraj &
S Thamarai Selvi* |
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1208 |
Solid phase deoximation of oximes to the
corresponding carbonyl compounds using bromate exchange resin |
Bromate Exchange resin (BRER) prepared by
simple elution technique has been used for deoximation of oximes to the
corresponding carbonyl compounds in biphasic condition. Reaction conditions
are simple and yields of the carbonyl compounds are high. |
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Atul P Sikdar &
Pranab J Das* |
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1211 |
Synthesis of some 4-substituted
hydrazinotetrazolo[1,5-a]quinoxalines |
The reaction of
4-hydrazinotetrazolo[1,5-a]quinoxaline with various aldehydes in DMF
gives 4-substituted hydrazinotetrazolo[1,5-a]quinoxalines. The
structures of compounds have been confirmed by IR and 1H NMR. |
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M B Deshmukh*, A R Mali, S D Jadhav & A W Suryawanshi |
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Authors for correspondence are indicated by (*) |
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