Total visitors:  since 25-5-05

Indian Journal of Chemistry

Sect. B: Organic Chemistry including Medicinal Chemistry





MAY 2005







Enantiospecific synthesis of sesquiterpenes from (R)-carvone. Synthesis of 3-thapsenol


 IPC: Int.Cl.7 C 07 13/08

Enantiospecific synthesis of thapsen-3-ol has been accomplished starting from (R)-carvone.





A Srikrishna* & K Anebouselvy



Synthesis, characterization of di-n-butyltin comp­ounds with (thiocarbamoylthio) acetic acid and crystal structure of {[n-Bu2Sn(O2CCH2CS2NC5H10)]2O}2·2H2O and n-Bu2Sn(O2CCH2CS2NC5H10)2


IPC: Int.Cl.7 C 07 327/00

The four di-n-butyltin compounds {[n-Bu2SnO2CCH2CS2NC5H10]2O}2·2H2O 1, n-Bu2Sn(O2CCH2CS2NC5H10)2 2, {[n-Bu2SnO2CCH2CS2N(CH3)C2H5]2O}2 3 and n-Bu2Sn(O2CCH2CS2N(CH3)C2H5)2 4 have been synthesized. The crystal and molecular structures of compounds 1 and 2 are determined by X-ray single crystal diffraction.





Handong Yin*, Shengcai Xue & Qibao Wang






2,4,5-Trichlorophenyl-(9H-fluoren-9ylmethoxy ­car ­bonyl­amino)methylcarbamates: Synthesis, isola­tion, characterization and utility in the synthesis of dipeptidyl ureas


IPC: Int.Cl.7 C 07 K

An efficient synthesis of 2,4,5-trichlorophenyl- (9H-fluoren-9-ylmethoxycarbonylamino)methylcarbamates employing isocyanates derived from several Fmoc-amino acids and 2,4,5-trichlorophenol has been described. All the carbamates made have been obtained as crystalline solids and are fully characterized by IR, 1H NMR, 13C NMR and mass spectrometry. Their utility for the synthesis of Fmoc-dipeptidyl urea esters and urea acids has also been described.





Vommina V Suresh Babu* & Kantharaju



Novel synthesis of substituted cyclopropane acetic acid ethyl esters from cyclopropyl alkyl ketones


 IPC: Int.Cl.7 C 07 C 13/04




Rishan Lang Nongkhlaw, Ridaphun Nongrum, Irona Nongkynrih, Felix Mathew Vattakunnel & Bekington Myrboh*



Revised synthesis of the pentasaccharide related to the repeating unit of the O-antigen from Shigella dysenteriae type-4 in the form of its methyl ester 2-(trimethylsilyl)ethyl glycoside


IPC: Int.Cl.7 C 07 H

A revised and simplified method has been developed for the synthesis of the pentasaccharide, namely methyl a-l-fucopyranosyl-(1®3)-2-acetamido-2-deoxy-a-d glucopyranosyl-(1®3)-2-acetamido-2-deoxy-4-O-(a-l-fucopyranosyl)-a-d-glucopyranosyl-(1®4)-[2 (tri­methyl­silyl)-ethyl b-d-glucopyranoside] uronate, related to the repeating unit of the O-antigen from Shigella dysenteriae type-4.





Sujit Kumar Sarkar, Balaram Mukhopadhyay & Nirmolendu Roy*



Cycloaddition reaction of 8-diazotheophylline with some dipolarophiles: Facile synthesis of new derivatives of 1,2,4-triazino[3,4-f]purine


IPC: Int.Cl.7 C 07 D 253/10






Mosselhi A N Mosselhi



1,3-Dipolar cycloaddition reactions: Synthesis and antimicrobial activity of novel 1-triazolyl­ethyl­indole and 1-triazolylethylbenz[g]indole derivatives


IPC: Int.Cl.7 C 07 D 209/04




Manjunath G Bhovi & Guru S Gadaginamath*



Synthesis and antimicrobial screening of N-[coumarin-6-ylamino]thiazolidinone and spiro indolo-thiazolidinone derivatives


IPC: Int.Cl.7 C 07 D 209/04 // A 61 P 31/04, 31/10

Synthetic utility of N-[coumarin-6-ylamino]-2-arylthiazolidine-4(H)-one 4, 1,2-dihydro-3-[coumarin-6-ylhydrazono]indol-2-one 5 and N-[coumarin-6-ylamino]spiro-[3H-indole-(1H,2H)-3,2-(4H)-thiazolidine ] -2,4-dione 6 as antibacterial and antifungal agents.



B P Choudhari & V V Mulwad*



Synthesis of 1-(6-methylbenzofuran-2-yl)-3-aryl/[4- (β-substitutedethoxy)phenyl]propenones as marked anti-microbial agents


IPC: Int.Cl.7 C 07 D // A 61 P31/04, 31/10

2-Acetyl-6-methylbenzofuran 1 has been synthesized under PTC conditions and conventional method (acetone/K2CO3). 1-(6-Methylbenzofuran-2-yl)-3-aryl­propenones 3a-e and 1-(6-methylbenzofuran-2-yl)-3-[4-(β-substitutedethoxy)phenyl]propenones 4a-e have also been synthesized.




Y Thirupathi Reddy*, P Narsimha Reddy,

Md Abdul Mannan, B Sunil Kumar & T Gururaj



Microwave-induced synthesis of fluorine contain­ing 1, 5-disubstituted hydantoins and thio­hydan­toins and their antibacterial activity


IPC: Int.Cl.7 C 07 D // A 61 P 31/04


Ten new fluorine containing 1, 5-disubstituted hydan­toins­/thio­hydantoins 3a-t have been synthe­sized by a microwave-assisted solvent-free condensa­tion of aryl­glyoxals 1 and phenylurea/thiourea 2 using acidic alumina as a solid support.



V M Patel & K R Desai*




New triterpenic esters of oleanene-series from the flowers of Calendula officinalis Linn.


IPC: Int.Cl.7 A 61 K 35/00


One new triterpenoid, cornulacic acid acetate 1 along with known oleanolic acid acetate 2 has been isolated from the flowers of Calendula officinalis Linn. The structure of 1 has been established as 3b-acetoxy-olean-12-en-27-oic acids on the basis of spectral data analysis and chemical reactions.



T Naved, S H Ansari*, H M Mukhtar & M Ali



Determining ring-F configuration in spirostane-type steroidal sapogenins by 1H NMR


IPC: Int.Cl.7 C 07 J

A 1H NMR method based upon the chemical shifts of the methylene protons occupying b and g has been proposed for the establishment 25R- and 25S-stereochemistry of spirostane-type steroidal sapogenins.



25R                                                                               25S



Pawan K Agrawal





Synthesis of novel 2,¢ 3¢-unsaturated nucleoside


IPC: Int.Cl.7 C 07 H

A synthetic approach for novel unsaturated nucleo­side has been presented.



Virendra Singh



Synthesis and structural characterization of dinuclear copper( II) complex [Cu2(C2O4)(2,2¢-bpy)2(H2O)2]·(NO3)2


IPC: Int.Cl.7 C 07 G 3/00

The complex [Cu2(C2O4)(2,2¢-bpy)2(H2O)2]·(NO3)2 has been synthesized and crystallographically studied.



L R Wen, M Li, W Wang, G L Zhao, X M Li, S S Zhang*, H Xu & P K Ouyang



Synthesis of 3-phenyl-4-oxopyrano[2,3-a]carbazoles (indoloisoflavones)


 IPC: Int.Cl.7 C 07 D 209/04



Text Box: 4




T Vandana & K J Rajendra Prasad*



A facile synthesis of 5-acylbarbituric acids under microwave irradiations


IPC: Int.Cl.7 C 07 D 239/62

Barbituric acids are benzoylated with benzoic anhydride at C-5 under microwave irradiations.





Palwinder Singh* & Kamaldeep Paul



Synthesis of benzo[b]furan Mannich bases under solventless, PTSA/PTC catalytic conditions assisted by microwave irradiation


IPC: Int.Cl.7 C 07 D 307/00

Condensation of 2-aroyl-6-hydroxy-3-methyl-5-acetyl-benzo[b]furan with different amines and paraformaldehyde in the presence of p-toluene sulfonic acid (PTSA) or PTC has been reported.





G V P Rao, P Narasimha Reddy, Y Thirupathi Reddy,

V Naveen Kumar & B Rajitha*


Synthesis and antimicrobial activity of 10N-{[(aryl)-amino]-methyl}-3-methoxy-10,10a–di­hy­dro -4a-H-phenothiazine-9-carboxylic acid


IPC: Int.Cl.7 C 07 D // A 61 P 31/04, 31/10

The title compounds 3a-r have been synthesised by the reaction of 3-methoxy-9-carboxyphenothiazine, formaldehyde and arylamine in the presence of hydro­chloric acid (Mannich reaction). The consti­tution of the products are  supported by IR, PMR and elemental analysis.





V R Radadiya, D M Purohit & V N Patolia*



Cyclodehydration reaction in water medium leads to library/multigram synthesis of 1,5-diaryl­pyra­zoles


IPC: Int.Cl.7 C 07 D // A 61 P 31/04, 31/10






V R Radadiya, D M Purohit & V N Patolia*



A substituted imidazole derivative from Jatropha curcas

 IPC: Int.Cl.7 C 07 D 233/54





Biswanath Das*, M Ravinder Reddy, N Ravindranath, K Hara Kishore & U S N Murthy


Authors for correspondence are indicated by (*)


IPC: International Patent Classification

Int. Cl.: International Classification 7 edition, 1999